Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha.
Recent investigations have identified a signal-transduction system involving sphingomyelin and derivatives. In this paradigm, sphingomyelin hydrolysis by a sphingomyelinase generates ceramide, which may be converted to the protein kinase C inhibitor sphingosine or to ceramide 1-phosphate. Ceramide m...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1991
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52856/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946418/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.10009 |
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