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Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis
The Hippo signaling pathway, also known as the Salvador–Warts–Hippo pathway, is a regulator of organ size. The pathway takes its name from the Drosophila protein kinase, Hippo (STK4/MST1 and STK3/MST2 in mammals), which, when inactivated, leads to considerable tissue overgrowth. In mammals, MST1 and...
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| Publicado no: | Gastroenterology |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5285449/ https://ncbi.nlm.nih.gov/pubmed/28003097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.10.047 |
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