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Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis

The Hippo signaling pathway, also known as the Salvador–Warts–Hippo pathway, is a regulator of organ size. The pathway takes its name from the Drosophila protein kinase, Hippo (STK4/MST1 and STK3/MST2 in mammals), which, when inactivated, leads to considerable tissue overgrowth. In mammals, MST1 and...

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Foilsithe in:Gastroenterology
Main Authors: Patel, Sachin, Camargo, Fernando D., Yimlamai, Dean
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285449/
https://ncbi.nlm.nih.gov/pubmed/28003097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.10.047
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