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Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis
The Hippo signaling pathway, also known as the Salvador–Warts–Hippo pathway, is a regulator of organ size. The pathway takes its name from the Drosophila protein kinase, Hippo (STK4/MST1 and STK3/MST2 in mammals), which, when inactivated, leads to considerable tissue overgrowth. In mammals, MST1 and...
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Foilsithe in: | Gastroenterology |
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Main Authors: | , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
2016
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5285449/ https://ncbi.nlm.nih.gov/pubmed/28003097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.10.047 |
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