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Hippo signalling controls Dronc activity to regulate organ size in Drosophila
The Hippo pathway controls organ size by multiple mechanisms that ultimately regulate the transcriptional co-activator Yorkie (Yki). Downregulation of Hippo signalling leads to tissue overgrowths due to Yki-mediated activation of target genes, whereas overexpression of the pathway triggers apoptosis...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3438497/ https://ncbi.nlm.nih.gov/pubmed/22555454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.48 |
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