Regulation of Sterol Biosynthesis in the Human Fungal Pathogen Aspergillus fumigatus: Opportunities for Therapeutic Development

Sterols are a major component of eukaryotic cell membranes. For human fungal infections caused by the filamentous fungus Aspergillus fumigatus, antifungal drugs that target sterol biosynthesis and/or function remain the standard of care. Yet, an understanding of A. fumigatus sterol biosynthesis regu...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Dhingra, Sourabh, Cramer, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285346/
https://ncbi.nlm.nih.gov/pubmed/28203225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00092
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