Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus

Ergothioneine (EGT; 2-mercaptohistidine trimethylbetaine) is a trimethylated and sulphurised histidine derivative which exhibits antioxidant properties. Here we report that deletion of Aspergillus fumigatus egtA (AFUA_2G15650), which encodes a trimodular enzyme, abrogated EGT biosynthesis in this op...

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Publicat a:Sci Rep
Autors principals: Sheridan, Kevin J., Lechner, Beatrix Elisabeth, Keeffe, Grainne O’, Keller, Markus A., Werner, Ernst R., Lindner, Herbert, Jones, Gary W., Haas, Hubertus, Doyle, Sean
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066259/
https://ncbi.nlm.nih.gov/pubmed/27748436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35306
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