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Nuclear Dynamics of Heterochromatin Repair

Repairing double-strand breaks (DSBs) is particularly challenging in pericentromeric heterochromatin, where the abundance of repeated sequences exacerbates the risk of ectopic recombination and chromosome rearrangements. Recent studies in Drosophila cells revealed that faithful homologous recombinat...

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Bibliografske podrobnosti
izdano v:Trends Genet
Main Authors: Amaral, Nuno, Ryu, Taehyun, Li, Xiao, Chiolo, Irene
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285325/
https://ncbi.nlm.nih.gov/pubmed/28104289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2016.12.004
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