Exogenous expression of SAMHD1 inhibits proliferation and induces apoptosis in cutaneous T-cell lymphoma-derived HuT78 cells

Sterile α motif and HD domain-containing protein 1 (SAMHD1) is a mammalian dNTP hydrolase (dNTPase) that regulates intracellular dNTP balance. We have previously reported that SAMHD1 mRNA and protein levels are significantly downregulated in CD4(+) T-cells of patients with cutaneous T-cell lymphoma...

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Publicado en:Cell Cycle
Main Authors: Kodigepalli, Karthik M., Li, Minghua, Liu, Shan-Lu, Wu, Li
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283819/
https://ncbi.nlm.nih.gov/pubmed/27929746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1261226
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