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Interleukin-2 Induces the Activities of DNA Topoisomerase I and DNA Topoisomerase II in HuT-78 Cells

The induction by interleukin-2 of DNA topoisomerase I and DNA topoisomerase II activities in the human T cell line HuT 78 was investigated. HuT 78 cells were treated with 1,000 units of interleukin-2/ml, and extracts of the HuT 78 nuclei were prepared over a 24 hour period. The extracts were assayed...

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Detalhes bibliográficos
Main Authors: Pham, Minh-Hieu, Kondapalli, Navya, Reckord, Calvin L., Foglesong, P. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789651/
https://ncbi.nlm.nih.gov/pubmed/19818738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.10.008
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