Poliovirus thiol proteinase 3C can utilize a serine nucleophile within the putative catalytic triad.
The picornavirus 3C proteinases are substrate-specific thiol proteases that have been shown by secondary structure predictions and protein modeling studies to be similar to the trypsin-like serine proteases. We have examined several mutations of the 3C proteinase at putative active site and non-acti...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1658804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.9919 |
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