Poliovirus thiol proteinase 3C can utilize a serine nucleophile within the putative catalytic triad.

The picornavirus 3C proteinases are substrate-specific thiol proteases that have been shown by secondary structure predictions and protein modeling studies to be similar to the trypsin-like serine proteases. We have examined several mutations of the 3C proteinase at putative active site and non-acti...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lawson, M A, Semler, B L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1658804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.9919
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