Dasatinib inhibits c-src phosphorylation and prevents the proliferation of Triple-Negative Breast Cancer (TNBC) cells which overexpress Syndecan-Binding Protein (SDCBP)

Triple negative breast cancer (TNBC) progresses rapidly but lacks effective targeted therapies. Our previous study showed that downregulating syndecan-binding protein (SDCBP) in TNBC inhibits the proliferation of TNBC cells. Dasatinib is a new small-molecule inhibitor of c-src phosphorylation. The a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Qian, Xiao-Long, Zhang, Jun, Li, Pei-Ze, Lang, Rong-Gang, Li, Wei-Dong, Sun, Hui, Liu, Fang-Fang, Guo, Xiao-Jing, Gu, Feng, Fu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283743/
https://ncbi.nlm.nih.gov/pubmed/28141839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171169
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