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Flow Cytometric Determination of Src Phosphorylation in Pediatric Patients Treated with Dasatinib

Tyrosine kinase inhibitors, such as imatinib, have dramatically improved the outcomes forpatients with selected cancers. For imatinib, western blotting of phospho-CrkL was an insensitive, indirect, and descriptive method to determine drug efficacy. Greater use of targeted therapies should involve mo...

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Bibliografske podrobnosti
Main Authors: Guerrouahen, Bella S., Wieder, Eric, Blanchard, Elisabeth G., Lee, Francis Y., Aplenc, Richard, Corey, Seth J.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760231/
https://ncbi.nlm.nih.gov/pubmed/19484755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22083
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