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Flow Cytometric Determination of Src Phosphorylation in Pediatric Patients Treated with Dasatinib
Tyrosine kinase inhibitors, such as imatinib, have dramatically improved the outcomes forpatients with selected cancers. For imatinib, western blotting of phospho-CrkL was an insensitive, indirect, and descriptive method to determine drug efficacy. Greater use of targeted therapies should involve mo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760231/ https://ncbi.nlm.nih.gov/pubmed/19484755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22083 |
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