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Flow Cytometric Determination of Src Phosphorylation in Pediatric Patients Treated with Dasatinib

Tyrosine kinase inhibitors, such as imatinib, have dramatically improved the outcomes forpatients with selected cancers. For imatinib, western blotting of phospho-CrkL was an insensitive, indirect, and descriptive method to determine drug efficacy. Greater use of targeted therapies should involve mo...

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Autori principali: Guerrouahen, Bella S., Wieder, Eric, Blanchard, Elisabeth G., Lee, Francis Y., Aplenc, Richard, Corey, Seth J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760231/
https://ncbi.nlm.nih.gov/pubmed/19484755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22083
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