Progressive APOBEC3B mRNA expression in distant breast cancer metastases

BACKGROUND: APOBEC3B was recently identified as a gain-of-function enzymatic source of mutagenesis, which may offer novel therapeutic options with molecules that specifically target this enzyme. In primary breast cancer, APOBEC3B mRNA is deregulated in a substantial proportion of cases and its expre...

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Bibliographic Details
Published in:	PLoS One
Main Authors:	Sieuwerts, Anieta M., Schrijver, Willemijne A. M. E., Dalm, Simone U., de Weerd, Vanja, Moelans, Cathy B., ter Hoeve, Natalie, van Diest, Paul J., Martens, John W. M., van Deurzen, Carolien H. M.
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2017
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5283735/ https://ncbi.nlm.nih.gov/pubmed/28141868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171343
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Progressive APOBEC3B mRNA expression in distant breast cancer metastases

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