Progressive APOBEC3B mRNA expression in distant breast cancer metastases

BACKGROUND: APOBEC3B was recently identified as a gain-of-function enzymatic source of mutagenesis, which may offer novel therapeutic options with molecules that specifically target this enzyme. In primary breast cancer, APOBEC3B mRNA is deregulated in a substantial proportion of cases and its expre...

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Udgivet i:PLoS One
Main Authors: Sieuwerts, Anieta M., Schrijver, Willemijne A. M. E., Dalm, Simone U., de Weerd, Vanja, Moelans, Cathy B., ter Hoeve, Natalie, van Diest, Paul J., Martens, John W. M., van Deurzen, Carolien H. M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283735/
https://ncbi.nlm.nih.gov/pubmed/28141868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171343
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