Progressive APOBEC3B mRNA expression in distant breast cancer metastases

BACKGROUND: APOBEC3B was recently identified as a gain-of-function enzymatic source of mutagenesis, which may offer novel therapeutic options with molecules that specifically target this enzyme. In primary breast cancer, APOBEC3B mRNA is deregulated in a substantial proportion of cases and its expre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sieuwerts, Anieta M., Schrijver, Willemijne A. M. E., Dalm, Simone U., de Weerd, Vanja, Moelans, Cathy B., ter Hoeve, Natalie, van Diest, Paul J., Martens, John W. M., van Deurzen, Carolien H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283735/
https://ncbi.nlm.nih.gov/pubmed/28141868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171343
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