PD-L1 (CD274) promoter methylation predicts survival in colorectal cancer patients

This study evaluates promoter methylation of the programmed cell death ligand 1 (PD-L1) as a biomarker in a cohort of 383 colorectal cancer patients. PD-L1 methylation (mPD-L1) was inversely correlated with PD-L1 mRNA expression (p = 0.001) and was associated with significantly shorter overall survi...

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Опубликовано в: :Oncoimmunology
Главные авторы: Goltz, Diane, Gevensleben, Heidrun, Dietrich, Jörn, Dietrich, Dimo
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2016
Предметы:
Brief Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283627/
https://ncbi.nlm.nih.gov/pubmed/28197377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1257454
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