CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels

Despite being one of the most studied proteases in bacteria, very little is known about the role of ClpXP in mitochondria. We now present evidence that mammalian CLPP has an essential role in determining the rate of mitochondrial protein synthesis by regulating the level of mitoribosome assembly. Th...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Szczepanowska, Karolina, Maiti, Priyanka, Kukat, Alexandra, Hofsetz, Eduard, Nolte, Hendrik, Senft, Katharina, Becker, Christina, Ruzzenente, Benedetta, Hornig‐Do, Hue‐Tran, Wibom, Rolf, Wiesner, Rudolf J, Krüger, Marcus, Trifunovic, Aleksandra
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283601/
https://ncbi.nlm.nih.gov/pubmed/27797820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694253
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