Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPR (mt)

The mitochondrial matrix protease CLPP plays a central role in the activation of the mitochondrial unfolded protein response (UPR (mt)) in Caenorhabditis elegans. Far less is known about mammalian UPR (mt) signaling, although similar roles were assumed for central players, including CLPP. To better...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Seiferling, Dominic, Szczepanowska, Karolina, Becker, Christina, Senft, Katharina, Hermans, Steffen, Maiti, Priyanka, König, Tim, Kukat, Alexandra, Trifunovic, Aleksandra
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Scientific Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931557/
https://ncbi.nlm.nih.gov/pubmed/27154400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642077
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