Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPR (mt)

The mitochondrial matrix protease CLPP plays a central role in the activation of the mitochondrial unfolded protein response (UPR (mt)) in Caenorhabditis elegans. Far less is known about mammalian UPR (mt) signaling, although similar roles were assumed for central players, including CLPP. To better...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO Rep
Päätekijät: Seiferling, Dominic, Szczepanowska, Karolina, Becker, Christina, Senft, Katharina, Hermans, Steffen, Maiti, Priyanka, König, Tim, Kukat, Alexandra, Trifunovic, Aleksandra
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Scientific Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931557/
https://ncbi.nlm.nih.gov/pubmed/27154400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642077
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