Central CCL2 signaling onto MCH neurons mediates metabolic and behavioral adaptation to inflammation

Sickness behavior defines the endocrine, autonomic, behavioral, and metabolic responses associated with infection. While inflammatory responses were suggested to be instrumental in the loss of appetite and body weight, the molecular underpinning remains unknown. Here, we show that systemic or centra...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Le Thuc, Ophélia, Cansell, Céline, Bourourou, Miled, Denis, Raphaël GP, Stobbe, Katharina, Devaux, Nadège, Guyon, Alice, Cazareth, Julie, Heurteaux, Catherine, Rostène, William, Luquet, Serge, Blondeau, Nicolas, Nahon, Jean‐Louis, Rovère, Carole
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283585/
https://ncbi.nlm.nih.gov/pubmed/27733491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541499
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