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Fatty acid binding profile of the liver X receptor α

Liver X receptor (LXR)α is a nuclear receptor that responds to oxysterols and cholesterol overload by stimulating cholesterol efflux, transport, conversion to bile acids, and excretion. LXRα binds to and is regulated by synthetic (T-0901317, GW3695) and endogenous (oxysterols) ligands. LXRα activity...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Bedi, Shimpi, Hines, Genesis Victoria, Lozada-Fernandez, Valery V., de Jesus Piva, Camila, Kaliappan, Alagammai, Rider, S. Dean, Hostetler, Heather A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282955/
https://ncbi.nlm.nih.gov/pubmed/28011707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M072447
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