A single amino acid change humanizes long-chain fatty acid binding and activation of mouse peroxisome proliferator-activated receptor α

Peroxisome proliferator-activated receptor α (PPARα) is an important regulator of hepatic lipid metabolism which functions through ligand binding. Despite high amino acid sequence identity (>90%), marked differences in PPARα ligand binding, activation and gene regulation have been noted across sp...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Oswal, Dhawal P., Alter, Gerald M., Rider, S. Dean, Hostetler, Heather A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079465/
https://ncbi.nlm.nih.gov/pubmed/24858253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2014.04.006
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares