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Peroxisome proliferator-activated receptor-α accelerates α-chlorofatty acid catabolism
α-Chlorofatty aldehydes are generated from myeloperoxidase-derived HOCl targeting plasmalogens, and are subsequently oxidized to α-chlorofatty acids (α-ClFAs). The catabolic pathway for α-ClFA is initiated by ω-oxidation. Here, we examine PPAR-α activation as a mechanism to increase α-ClFA catabolis...
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| Publicado no: | J Lipid Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5282948/ https://ncbi.nlm.nih.gov/pubmed/28007964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M069740 |
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