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α-Chlorofatty acid accumulates in activated monocytes and causes apoptosis through reactive oxygen species production and endoplasmic reticulum stress
OBJECTIVE: Myeloperoxidase-enriched monocytes play important roles in inflammatory disease such as atherosclerosis. We previously demonstrated α-chlorofatty aldehydes (α-ClFALD) are produced as a result of plasmalogen targeting by myeloperoxidase-derived hypochlorous acid (HOCl) in activated monocyt...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951512/ https://ncbi.nlm.nih.gov/pubmed/24371082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302544 |
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