A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease

Pre‐B‐cell leukemia homeobox (PBX) transcription factors are known to regulate organogenesis, but their molecular targets and function in midbrain dopaminergic neurons (mDAn) as well as their role in neurodegenerative diseases are unknown. Here, we show that PBX1 controls a novel transcriptional net...

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Publicado en:EMBO J
Autores principales: Villaescusa, J Carlos, Li, Bingsi, Toledo, Enrique M, Rivetti di Val Cervo, Pia, Yang, Shanzheng, Stott, Simon RW, Kaiser, Karol, Islam, Saiful, Gyllborg, Daniel, Laguna‐Goya, Rocio, Landreh, Michael, Lönnerberg, Peter, Falk, Anna, Bergman, Tomas, Barker, Roger A, Linnarsson, Sten, Selleri, Licia, Arenas, Ernest
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282836/
https://ncbi.nlm.nih.gov/pubmed/27354364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593725
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