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Epigenetics of oropharyngeal squamous cell carcinoma: opportunities for novel chemotherapeutic targets

Epigenetic modifications are heritable changes in gene expression that do not directly alter DNA sequence. These modifications include DNA methylation, histone post-translational modifications, small and non-coding RNAs. Alterations in epigenetic profiles cause deregulation of fundamental gene expre...

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Bibliographic Details
Published in:J Otolaryngol Head Neck Surg
Main Authors: Lindsay, Cameron, Seikaly, Hadi, Biron, Vincent L.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282807/
https://ncbi.nlm.nih.gov/pubmed/28143553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40463-017-0185-3
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