Investigation of EZH2 pathways for novel epigenetic treatment strategies in oropharyngeal cancer

BACKGROUND: In recent decades, the incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been rising worldwide as a result of increasing oncogenic human papillomavirus (HPV) infections in the oropharynx. EZH2 is an epigenetic regulatory protein associated with tumor aggressiveness and negat...

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Detalhes bibliográficos
Publicado no:J Otolaryngol Head Neck Surg
Main Authors: Idris, Sherif, Lindsay, Cameron, Kostiuk, Morris, Andrews, Colin, Côté, David W. J., O’Connell, Daniel A., Harris, Jeffrey, Seikaly, Hadi, Biron, Vincent L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084374/
https://ncbi.nlm.nih.gov/pubmed/27793210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40463-016-0168-9
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