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SkfB abstracts a hydrogen atom from C(α) on SkfA to initiate thioether crosslink formation

Sulfur to alpha carbon thioether-containing peptides (sactipeptides) are ribosomally synthesized post-translationally modified peptides (RiPPs) with bacteriocidal activities. The thioether crosslink, which is required for biological activity, is installed by a member of the radical S-adenosyl-l-meth...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Bruender, Nathan A., Bandarian, Vahe
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282607/
https://ncbi.nlm.nih.gov/pubmed/27410522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00598
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