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Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome

Transcriptional variation in histologically- and genetically- identical cells is a widespread phenomenon in tissues, yet the processes conferring this heterogeneity are not well understood. To identify contributing factors, we analyzed epigenetic profiles associated with the in vivo transcriptional...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oh, Edward, Jeremian, Richie, Oh, Gabriel, Groot, Daniel, Susic, Miki, Lee, KwangHo, Foy, Kelly, Laird, Peter W., Petronis, Arturas, Labrie, Viviane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282553/
https://ncbi.nlm.nih.gov/pubmed/28139744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41843
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