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Deferasirox-induced iron depletion promotes BclxL downregulation and death of proximal tubular cells
Iron deficiency has been associated with kidney injury. Deferasirox is an oral iron chelator used to treat blood transfusion-related iron overload. Nephrotoxicity is the most serious and common adverse effect of deferasirox and may present as an acute or chronic kidney disease. However, scarce data...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5282523/ https://ncbi.nlm.nih.gov/pubmed/28139717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41510 |
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