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RNA Interference of Human α-Synuclein in Mouse
α-Synuclein is postulated to play a key role in the pathogenesis of Parkinson’s disease (PD). Aggregates of α-synuclein contribute to neurodegeneration and cell death in humans and in mouse models of PD. Here, we use virally mediated RNA interference to knockdown human α-synuclein in mice. We used a...
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| Pubblicato in: | Front Neurol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5281542/ https://ncbi.nlm.nih.gov/pubmed/28197125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00013 |
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