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Recent Advances in RNA Interference Therapeutics for CNS Diseases

Over the last decade, RNA interference technology has shown therapeutic promise in rodent models of dominantly inherited brain diseases, including those caused by polyglutamine repeat expansions in the coding region of the affected gene. For some of these diseases, proof-of concept studies in model...

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Autors principals: Ramachandran, Pavitra S., Keiser, Megan S., Davidson, Beverly L.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701762/
https://ncbi.nlm.nih.gov/pubmed/23589092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0183-8
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