Stress Response Gene Nupr1 Alleviates Cyclosporin A Nephrotoxicity In Vivo

Acute tubular damage is a major cause of renal failure, especially at the early phase of kidney transplant when ischemia-reperfusion injury and cyclosporin A toxicity may coexist. The mechanisms of the latter are largely unknown. Using an mRNA microarray on microdissected tubules from a rat model of...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Galichon, Pierre, Bataille, Aurélien, Vandermeersch, Sophie, Wetzstein, Morgane, Xu-Dubois, Yi-Chun, Legouis, David, Hertig, Alexandre, Buob, David, Placier, Sandrine, Bigé, Naïke, Lefevre, Guillaume, Jouanneau, Chantal, Martin, Caroline, Iovanna, Juan Lucio, Rondeau, Eric
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2017
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5280006/
https://ncbi.nlm.nih.gov/pubmed/27451286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015080936
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