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Inhibition of Bromodomain and Extraterminal Domain Family Proteins Ameliorates Experimental Renal Damage

Renal inflammation has a key role in the onset and progression of immune– and nonimmune–mediated renal diseases. Therefore, the search for novel anti–inflammatory pharmacologic targets is of great interest in renal pathology. JQ1, a small molecule inhibitor of bromodomain and extraterminal (BET) pro...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Suarez-Alvarez, Beatriz, Morgado-Pascual, José Luis, Rayego-Mateos, Sandra, Rodriguez, Ramon M., Rodrigues-Diez, Raul, Cannata-Ortiz, Pablo, Sanz, Ana B., Egido, Jesus, Tharaux, Pierre-Louis, Ortiz, Alberto, Lopez-Larrea, Carlos, Ruiz-Ortega, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5280004/
https://ncbi.nlm.nih.gov/pubmed/27436852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015080910
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