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KetoABNO/NO(x) Co-Catalytic Aerobic Oxidation of Aldehydes to Carboxylic Acids and Access to α-Chiral Carboxylic Acids via Sequential Asymmetric Hydroformylation/Oxidation

A method for aerobic oxidation of aldehydes to carboxylic acids has been developed using organic nitroxyl and NO(x) co-catalysts. KetoABNO (9-azabicyclo[3.3.1]nonan-3-one N-oxyl) and NaNO(2) were identified as the optimal nitroxyl and NO(x) sources, respectively. The mildness of the reaction conditi...

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Publicat a:Org Lett
Autors principals: Miles, Kelsey C., Abrams, M. Leigh, Landis, Clark R., Stahl, Shannon S.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279997/
https://ncbi.nlm.nih.gov/pubmed/27410397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b01598
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