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In Vitro Characterization and In Vivo Ultrasound Molecular Imaging of Nucleolin-Targeted Microbubbles

Nucleolin (NCL) plays an important role in tumor vascular development. An increased endothelial expression level of NCL has been related to cancer aggressiveness and prognosis and has been detected clinically in advanced tumors. Here, with a peptide targeted to NCL (F3 peptide), we created an NCL-ta...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Zhang, Hua, Ingham, Elizabeth S., Gagnon, M. Karen J., Mahakian, Lisa M., Liu, Jingfei, Foiret, Josquin L., Willmann, Juergen K., Ferrara, Katherine W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279957/
https://ncbi.nlm.nih.gov/pubmed/27940383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.11.026
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