In Vitro Characterization and In Vivo Ultrasound Molecular Imaging of Nucleolin-Targeted Microbubbles

Nucleolin (NCL) plays an important role in tumor vascular development. An increased endothelial expression level of NCL has been related to cancer aggressiveness and prognosis and has been detected clinically in advanced tumors. Here, with a peptide targeted to NCL (F3 peptide), we created an NCL-ta...

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Veröffentlicht in:Biomaterials
Hauptverfasser: Zhang, Hua, Ingham, Elizabeth S., Gagnon, M. Karen J., Mahakian, Lisa M., Liu, Jingfei, Foiret, Josquin L., Willmann, Juergen K., Ferrara, Katherine W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279957/
https://ncbi.nlm.nih.gov/pubmed/27940383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.11.026
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