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Obinutuzumab in chronic lymphocytic leukemia: design, development and place in therapy

For decades, treatment of chronic lymphocytic leukemia (CLL) has been based on chemotherapy. This changed when the first CD20 antibody rituximab was introduced. Since 2008, the combination of chemotherapy and CD20 antibodies has become the standard of care for most patients, and a significant fracti...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Al-Sawaf, Othman, Fischer, Kirsten, Engelke, Anja, Pflug, Natali, Hallek, Michael, Goede, Valentin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279834/
https://ncbi.nlm.nih.gov/pubmed/28182141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S104869
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