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Obinutuzumab in chronic lymphocytic leukemia: design, development and place in therapy

For decades, treatment of chronic lymphocytic leukemia (CLL) has been based on chemotherapy. This changed when the first CD20 antibody rituximab was introduced. Since 2008, the combination of chemotherapy and CD20 antibodies has become the standard of care for most patients, and a significant fracti...

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Bibliografiska uppgifter
I publikationen:Drug Des Devel Ther
Huvudupphovsmän: Al-Sawaf, Othman, Fischer, Kirsten, Engelke, Anja, Pflug, Natali, Hallek, Michael, Goede, Valentin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279834/
https://ncbi.nlm.nih.gov/pubmed/28182141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S104869
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