Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice

Peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) inhibits steatosis and inflammation, known risk factors for liver cancer. In this study, the effect of ligand activation of PPARβ/δ in modulating liver tumorigenesis in transgenic hepatitis B virus (HBV) mice was examined. Activation of PPARβ/...

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Pubblicato in:Toxicology
Autori principali: Balandaram, Gayathri, Kramer, Lance R., Kang, Boo-Hyon, Murray, Iain A., Perdew, Gary H., Gonzalez, Frank J., Peters, Jeffrey M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278792/
https://ncbi.nlm.nih.gov/pubmed/27427494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2016.07.010
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