A Naturally Occurring Single Nucleotide Polymorphism in a Multicopy Plasmid Produces a Reversible Increase in Antibiotic Resistance

ColE1 plasmids are small mobilizable replicons that play an important role in the spread of antibiotic resistance in Pasteurellaceae. In this study, we describe how a natural single nucleotide polymorphism (SNP) near the origin of replication of the ColE1-type plasmid pB1000 found in a Pasteurella m...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Santos-Lopez, Alfonso, Bernabe-Balas, Cristina, Ares-Arroyo, Manuel, Ortega-Huedo, Rafael, Hoefer, Andreas, San Millan, Alvaro, Gonzalez-Zorn, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278757/
https://ncbi.nlm.nih.gov/pubmed/27895020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01735-16
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