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Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Multicopy plasmids are extremely abundant in prokaryotes but their role in bacterial evolution remains poorly understood. We recently showed that the increase in gene copy number per cell provided by multicopy plasmids could accelerate the evolution of plasmid-encoded genes. In this work, we present...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Escudero, Jose Antonio, MacLean, R Craig, San Millan, Alvaro
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101099/
https://ncbi.nlm.nih.gov/pubmed/29781985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57386
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