Evaluation of Doravirine Pharmacokinetics When Switching from Efavirenz to Doravirine in Healthy Subjects

Doravirine is a novel, potent nonnucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of patients with human immunodeficiency virus type 1 (HIV-1) infection that demonstrates a high genetic barrier to resistance and that has been well tolerated in studies to date. Doravirine is a can...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Yee, Ka Lai, Sanchez, Rosa I., Auger, Patrice, Liu, Rachael, Fan, Li, Triantafyllou, Ilias, Lai, Ming-Tain, Di Spirito, Mike, Iwamoto, Marian, Khalilieh, Sauzanne G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278744/
https://ncbi.nlm.nih.gov/pubmed/27872069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01757-16
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