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Doravirine Exposure and HIV-1 Suppression after Switching from an Efavirenz-Based Regimen to Doravirine-Lamivudine-Tenofovir Disoproxil Fumarate

Doravirine is a nonnucleoside reverse transcriptase inhibitor that has been approved for the treatment of HIV-1. In a phase 1 trial, doravirine exposure was transiently decreased when treatment was started immediately after the cessation of efavirenz treatment. In a post hoc subgroup analysis of par...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Greaves, Wayne, Wan, Hong, Yee, Ka Lai, Kandala, Bhargava, Vaddady, Pavan, Hwang, Carey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879224/
https://ncbi.nlm.nih.gov/pubmed/31548188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01298-19
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