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Selective Induction of P-glycoprotein at the CNS Barriers during Symptomatic Stage of an ALS Animal Model
P-glycoprotein (P-gp), Breast cancer resistance protein (BCRP) and Multidrug resistance-associated protein 2 (MRP2) residing at the blood-brain barrier (BBB) and the blood-spinal cord barrier (BSCB) are major obstacles for drug delivery to the Central Nervous System (CNS). Disease-induced changes of...
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| Izdano u: | Neurosci Lett |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5278641/ https://ncbi.nlm.nih.gov/pubmed/28011392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2016.12.049 |
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