Selective Induction of P-glycoprotein at the CNS Barriers during Symptomatic Stage of an ALS Animal Model

P-glycoprotein (P-gp), Breast cancer resistance protein (BCRP) and Multidrug resistance-associated protein 2 (MRP2) residing at the blood-brain barrier (BBB) and the blood-spinal cord barrier (BSCB) are major obstacles for drug delivery to the Central Nervous System (CNS). Disease-induced changes of...

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Bibliografiset tiedot
Julkaisussa:Neurosci Lett
Päätekijät: Chan, Gary N.Y., Evans, Rebecca, Banks, David, Mesev, Emily, Miller, David S., Cannon, Ronald E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278641/
https://ncbi.nlm.nih.gov/pubmed/28011392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2016.12.049
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