SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense

Excess in mitochondrial reactive oxygen species (ROS) is considered as a major cause of cellular oxidative stress. NADPH, the main intracellular reductant, has a key role in keeping glutathione in its reduced form GSH, which scavenges ROS and thus protects the cell from oxidative damage. Here, we re...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Zhou, Lisha, Wang, Fang, Sun, Renqiang, Chen, Xiufei, Zhang, Mengli, Xu, Qi, Wang, Yi, Wang, Shiwen, Xiong, Yue, Guan, Kun‐Liang, Yang, Pengyuan, Yu, Hongxiu, Ye, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278614/
https://ncbi.nlm.nih.gov/pubmed/27113762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541643
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados