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UBQLN4 recognizes mislocalized transmembrane domain proteins and targets these to proteasomal degradation
The majority of transmembrane proteins are integrated into the endoplasmic reticulum (ER) by virtue of a signal sequence‐mediated co‐translational process. However, a substantial portion of transmembrane proteins fails to reach the ER, leading to mislocalized cytosolic polypeptides. Their appropriat...
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| Publicado no: | EMBO Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5278606/ https://ncbi.nlm.nih.gov/pubmed/27113755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541402 |
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