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Stromal hedgehog signaling maintains smooth muscle and hampers micro-invasive prostate cancer

It is widely appreciated that reactive stroma or carcinoma-associated fibroblasts can influence epithelial tumor progression. In prostate cancer (PCa), the second most common male malignancy worldwide, the amount of reactive stroma is variable and has predictive value for tumor recurrence. By analyz...

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Dettagli Bibliografici
Pubblicato in:Dis Model Mech
Autori principali: Yang, Zhaohui, Peng, Yu-Ching, Gopalan, Anuradha, Gao, Dong, Chen, Yu, Joyner, Alexandra L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278527/
https://ncbi.nlm.nih.gov/pubmed/27935821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.027417
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