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Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle

Calsequestrin, the only known protein with cyclical storage and supply of calcium as main role, is proposed to have other functions, which remain unproven. Voluntary movement and the heart beat require this calcium flow to be massive and fast. How does calsequestrin do it? To bind large amounts of c...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Manno, Carlo, Figueroa, Lourdes C., Gillespie, Dirk, Fitts, Robert, Kang, ChulHee, Franzini-Armstrong, Clara, Rios, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278470/
https://ncbi.nlm.nih.gov/pubmed/28069951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620265114
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