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REV-ERBα regulates Fgf21 expression in the liver via hepatic nuclear factor 6
The circadian clock contributes to the timing of many body functions including metabolism and reproduction. The hepatokine fibroblast growth factor 21 (FGF21) is a critical metabolic regulator involved in modulation of fertility. Here we show that lack of the clock component REV-ERBα elevates FGF21...
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| Publicado no: | Biol Open |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5278426/ https://ncbi.nlm.nih.gov/pubmed/27875243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.021519 |
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