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Spheroid arrays for high-throughput single-cell analysis of spatial patterns and biomarker expression in 3D
We describe and share a device, methodology and image analysis algorithms, which allow up to 66 spheroids to be arranged into a gel-based array directly from a culture plate for downstream processing and analysis. Compared to processing individual samples, the technique uses 11-fold less reagents, s...
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| Publicat a: | Sci Rep |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5278392/ https://ncbi.nlm.nih.gov/pubmed/28134245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41160 |
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